The key advantage of this apartment is its location, in an area aside from the touristic flow, still peopled by Venetians (there are 2 gondoliers living in the building).
A few celebrities, including Casanova, Goldoni, and, surprisingly enough, Nietzsche, used to live in the same street - Calle della Testa.
There is a bakery and a supermarket less than 100 m away, together with local pubs still patronized by Venetians. It takes less than 10 minutes walking to Rialto and to San Marco Square.
Just round the corner, you will find the San Giovanni e Paolo church, which is the Westminster of Venetians, full of graves of Doges, heroes of the Serenissima like Marcantonio Bragadin, governor of Cyprus, who fought the Ottomans to the last shortly before Lepanto, or the Bandiera Brothers of the Risorgimento. But also filled with masterpieces of Titian, Bellini, Vivarini, Veronese, Palma and other artists.
You will appreciate having a cappucino at Rosa Salva on Campo San Giovanni e Paolo, while having a look at the equestrian statue of Coleoni, a proud 15th century condottiere who would have been a general anywhere anytime.
Access from and to the airport is really easy through the Fondamente Nuove vaporetti station which is the closest to the apartment, less than 5 minutes walking. The same for visiting the lagoon islands, of which I recommend Torcello and Burano.